Processing of novel bioactive polymeric matrixes for tissue engineering using supercritical fluid technology
نویسندگان
چکیده
منابع مشابه
Bioactive polymeric scaffolds for tissue engineering
A variety of engineered scaffolds have been created for tissue engineering using polymers, ceramics and their composites. Biomimicry has been adopted for majority of the three-dimensional (3D) scaffold design both in terms of physicochemical properties, as well as bioactivity for superior tissue regeneration. Scaffolds fabricated via salt leaching, particle sintering, hydrogels and lithography ...
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Recently, Supercritical fluids have been used in material synthesis and processing because of their special properties such as high diffusivity, low viscosity, and low surface tension. Supercritical carbon dioxide is the most attractive because it is non-toxic, non-flammable, and has moderate critical temperature and critical pressure. Moreover, and can also swell most polymers. In this study, ...
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Tissue engineering (TE) is an emerging field aimed at repairing defective tissues and organ, instead of relying on conventional organ transplantation. Among the polymeric materials proposed for TE applications, the water-soluble polymers have been frequently used in form of hydrogels, that are a class of highly hydrated polymer materials. Nevertheless, hydrogel materials have poor mechanical pr...
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Tissue engineering scaffolds require a controlled pore size and structure to host tissue formation. Supercritical carbon dioxide (scCO2) processing may be used to form foamed scaffolds in which the escape of CO2 from a plasticized polymer melt generates gas bubbles that shape the developing pores. The process of forming these scaffolds involves a simultaneous change in phase in the CO2 and the ...
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Objective(s): The present study aimed to prepare polycaprolactone (PCL) scaffolds with high porosity and pore interconnectivity, in order to copy the microstructure of natural bones using the thermally induced phase separation (TIPS) technique. Materials and Methods: The scaffolds were coated with chitosan (CH), bioactive glass (BG), and gelatin nanoparticles (GEL NPs) and assessed using ...
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ژورنال
عنوان ژورنال: Materials Science and Engineering: C
سال: 2009
ISSN: 0928-4931
DOI: 10.1016/j.msec.2009.04.012